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BRENDA support

Literature summary for 1.11.1.23 extracted from

  • Cameron, S.; McLuskey, K.; Chamberlayne, R.; Hallyburton, I.; Hunter, W.N.
    Initiating a crystallographic analysis of recombinant (S)-2-hydroxypropylphosphonic acid epoxidase from Streptomyces wedmorensis (2005), Acta Crystallogr. Sect. F, 61, 534-536.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
-
Streptomyces wedmorensis

Crystallization (Commentary)

Crystallization (Comment) Organism
vapour diffusion method. The hexagonal form displays symmetry consistent with space group P6(1/5)22 and unit-cell parameters a = 86.44, c = 221.56 A, gamma = 120° Streptomyces wedmorensis

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
21400
-
4 * 21400, crystalligraphic data Streptomyces wedmorensis

Organism

Organism UniProt Comment Textmining
Streptomyces wedmorensis Q56185
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-2-hydroxypropylphosphonic acid + 2 NADH + O2
-
Streptomyces wedmorensis cis-(1R,2S)-epoxypropylphosphonic acid + 2 H2O + 2 NAD+ i.e. fosfomycin ?

Subunits

Subunits Comment Organism
homotetramer 4 * 21400, crystalligraphic data Streptomyces wedmorensis