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Literature summary for 1.11.1.12 extracted from

  • Herbette, S.; Lenne, C.; Leblanc, N.; Julien, J.L.; Drevet, J.R.; Roeckel-Drevet, P.
    Two GPX-like proteins from Lycopersicon esculentum and Helianthus annuus are antioxidant enzymes with phospholipid hydroperoxide glutathione peroxidase and thioredoxin peroxidase activities (2002), Eur. J. Biochem., 269, 2414-2420.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Solanum lycopersicum

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0121
-
phosphatidylcholine dilinoleoyl hydroperoxide
-
Solanum lycopersicum
0.0249
-
phosphatidylcholine dilinoleoyl hydroperoxide
-
Solanum lycopersicum
0.0393
-
linoleic acid hydroperoxide
-
Solanum lycopersicum
0.0827
-
linoleic acid hydroperoxide
-
Solanum lycopersicum
0.0953
-
tert-butyl hydroperoxide
-
Solanum lycopersicum
0.119
-
cumene hydroperoxide
-
Solanum lycopersicum
0.128
-
tert-butyl hydroperoxide
-
Solanum lycopersicum
608
-
cumene hydroperoxide
-
Solanum lycopersicum

Organism

Organism UniProt Comment Textmining
Solanum lycopersicum
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GSH + cumene hydroperoxide
-
Solanum lycopersicum GSSG + ?
-
?
GSH + linoleic acid hydroperoxide
-
Solanum lycopersicum GSSG + ?
-
?
GSH + phosphatidylcholine dilinoleoyl hydroperoxide
-
Solanum lycopersicum GSSG + ?
-
?
GSH + tert-butyl hydroperoxide
-
Solanum lycopersicum GSSG + ?
-
?
additional information the enzyme shows phospholipid hydroperoxide glutathione peroxidase activity and thioredoxin peroxidase activity. Thioredoxin peroxidase activity is higher than phospholipid hydroperoxidase activity in terms of efficiency and substrate affinities. No activity with glutathione + H2O2 Solanum lycopersicum ?
-
?

Synonyms

Synonyms Comment Organism
GPXhs2
-
Solanum lycopersicum
GPXle1
-
Solanum lycopersicum