KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | detailed kinetics, overview | Neurospora crassa | |
additional information | - |
additional information | detailed kinetics, overview | Agaricus bisporus | |
additional information | - |
additional information | detailed kinetics, overview | Streptomyces glaucescens | |
0.28 | - |
dopamine | - |
Neurospora crassa | |
0.3 | - |
catechol | - |
Agaricus bisporus | |
0.38 | - |
D-Dopa | - |
Neurospora crassa | |
0.57 | - |
L-3,4-dihydroxyphenylalanine methyl ester | - |
Agaricus bisporus | |
0.74 | - |
chlorogenic acid | - |
Streptomyces glaucescens | |
0.8 | - |
L-Dopa | - |
Agaricus bisporus | |
0.91 | - |
tert-butylcatechol | - |
Streptomyces glaucescens | |
1.04 | - |
L-Dopa | - |
Neurospora crassa | |
1.05 | - |
3,4-dihydroxyphenyl propionic acid | - |
Streptomyces glaucescens | |
1.16 | - |
3,4-Dihydroxyphenyl acetic acid | - |
Streptomyces glaucescens | |
1.89 | - |
3,4-dihydroxyphenyl propionic acid | - |
Agaricus bisporus | |
1.9 | - |
4-methylcatechol | - |
Streptomyces glaucescens | |
2.16 | - |
1,2,3-benzenetriol | - |
Agaricus bisporus | |
2.2 | - |
dopamine | - |
Agaricus bisporus | |
2.36 | - |
4-methylcatechol | - |
Agaricus bisporus | |
2.8 | - |
tert-butylcatechol | - |
Agaricus bisporus | |
4.4 | - |
3,4-Dihydroxyphenyl acetic acid | - |
Neurospora crassa | |
4.5 | - |
catechol | - |
Streptomyces glaucescens | |
4.5 | - |
D-Dopa | - |
Agaricus bisporus | |
5.1 | - |
3,4-Dihydroxyphenyl acetic acid | - |
Agaricus bisporus | |
5.77 | - |
L-Dopa | - |
Streptomyces glaucescens | |
6.8 | - |
L-2-methyl-3,4-dihydroxyphenylalanine | - |
Agaricus bisporus | |
7.1 | - |
L-isoproterenol | - |
Agaricus bisporus | |
8 | - |
D-2-methyl-3,4-dihydroxyphenylalanine | - |
Agaricus bisporus | |
11.9 | - |
dopamine | - |
Streptomyces glaucescens | |
15.02 | - |
D-Dopa | - |
Streptomyces glaucescens | |
18.1 | - |
D-isoproterenol | - |
Agaricus bisporus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Cu2+ | copper enzyme | Neurospora crassa | |
Cu2+ | copper enzyme | Agaricus bisporus | |
Cu2+ | copper enzyme | Streptomyces glaucescens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Agaricus bisporus | - |
- |
- |
Neurospora crassa | - |
- |
- |
Streptomyces glaucescens | - |
- |
- |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Neurospora crassa |
additional information | - |
- |
Agaricus bisporus |
additional information | - |
- |
Streptomyces glaucescens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 D-isoproterenol + O2 | - |
Agaricus bisporus | 2 4-[(1S)-1-hydroxy-2-[(propan-2-yl)amino]ethyl]cyclohexa-3,5-diene-1,2-dione + 2 H2O | - |
r | |
3,4-dihydroxyphenyl acetic acid + O2 | - |
Neurospora crassa | ? | - |
? | |
3,4-dihydroxyphenyl acetic acid + O2 | - |
Agaricus bisporus | ? | - |
? | |
3,4-dihydroxyphenyl acetic acid + O2 | - |
Streptomyces glaucescens | ? | - |
? | |
3,4-dihydroxyphenyl propionic acid + O2 | - |
Agaricus bisporus | ? | - |
r | |
3,4-dihydroxyphenyl propionic acid + O2 | - |
Streptomyces glaucescens | ? | - |
? | |
4-methylcatechol + O2 | - |
Agaricus bisporus | 4-methyl-1,2-benzoquinone + H2O | - |
? | |
4-methylcatechol + O2 | - |
Streptomyces glaucescens | 4-methyl-1,2-benzoquinone + H2O | - |
? | |
5-caffeoyl quinic acid + O2 | i.e. chlorogenic acid | Streptomyces glaucescens | ? | - |
? | |
catechol + 1/2 O2 | - |
Agaricus bisporus | 1,2-benzoquinone + H2O | - |
? | |
catechol + 1/2 O2 | - |
Streptomyces glaucescens | 1,2-benzoquinone + H2O | - |
? | |
chlorogenic acid + O2 | - |
Streptomyces glaucescens | ? | - |
? | |
D-2-methyl-3,4-dihydroxyphenylalanine + O2 | - |
Agaricus bisporus | 2-methyldopaquinone + H2O | - |
r | |
D-dopa + 1/2 O2 | - |
Neurospora crassa | D-dopaquinone + H2O | - |
? | |
D-dopa + 1/2 O2 | - |
Agaricus bisporus | D-dopaquinone + H2O | - |
? | |
D-dopa + 1/2 O2 | - |
Streptomyces glaucescens | D-dopaquinone + H2O | - |
? | |
D-isoproterenol + O2 | - |
Agaricus bisporus | ? | - |
? | |
DL-2-methyl-3,4-dihydroxyphenylalanine + O2 | the L-isomer is preferred | Agaricus bisporus | 2-methyldopaquinone + H2O | - |
? | |
DL-DOPA + O2 | i.e. DL-3,4-dihydroxyphenylalanine, the L-isomer is preferred | Neurospora crassa | dopaquinone + H2O | - |
? | |
DL-DOPA + O2 | i.e. DL-3,4-dihydroxyphenylalanine, the L-isomer is preferred | Agaricus bisporus | dopaquinone + H2O | - |
? | |
DL-DOPA + O2 | i.e. DL-3,4-dihydroxyphenylalanine, the L-isomer is preferred | Streptomyces glaucescens | dopaquinone + H2O | - |
? | |
DL-isoproterenol + O2 | the L-isomer is preferred | Agaricus bisporus | ? | - |
? | |
dopamine + O2 | - |
Neurospora crassa | ? | - |
? | |
dopamine + O2 | - |
Agaricus bisporus | ? | - |
? | |
dopamine + O2 | - |
Streptomyces glaucescens | ? | - |
? | |
L-2-methyl-3,4-dihydroxyphenylalanine + O2 | - |
Agaricus bisporus | 2-methyldopaquinone + H2O | - |
r | |
L-3,4-dihydroxyphenylalanine methyl ester + 1/2 O2 | - |
Agaricus bisporus | L-dopaquinone methyl ester + H2O | - |
? | |
L-tyrosine + L-dopa + O2 | - |
Neurospora crassa | L-dopa + dopaquinone + H2O | - |
? | |
L-tyrosine + L-dopa + O2 | - |
Streptomyces glaucescens | L-dopa + dopaquinone + H2O | - |
? | |
additional information | the enzyme catalyzes the hydroxylation of monophenols to o-diphenols, monophenolase activity EC 1.14.18.1, and the oxidation of the o-diphenols to o-quinones, diphenolase activity EC 1.10.3.1, cross-reaction analysis, overview | Neurospora crassa | ? | - |
? | |
additional information | the enzyme catalyzes the hydroxylation of monophenols to o-diphenols, monophenolase activity EC 1.14.18.1, and the oxidation of the o-diphenols to o-quinones, diphenolase activity EC 1.10.3.1, cross-reaction analysis, overview | Agaricus bisporus | ? | - |
? | |
additional information | the enzyme catalyzes the hydroxylation of monophenols to o-diphenols, monophenolase activity EC 1.14.18.1, and the oxidation of the o-diphenols to o-quinones, diphenolase activity EC 1.10.3.1, cross-reaction analysis, overview | Streptomyces glaucescens | ? | - |
? | |
pyrogallol + O2 | - |
Agaricus bisporus | ? | - |
? | |
tert-butylcatechol + O2 | - |
Agaricus bisporus | ? | - |
? | |
tert-butylcatechol + O2 | - |
Streptomyces glaucescens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
mettyrosinase | - |
Neurospora crassa |
mettyrosinase | - |
Agaricus bisporus |
mettyrosinase | - |
Streptomyces glaucescens |
More | cf. 1.14.18.1 | Neurospora crassa |
More | cf. 1.14.18.1 | Agaricus bisporus |
More | cf. EC 1.14.18.1 | Streptomyces glaucescens |
o-diphenolase | - |
Neurospora crassa |
o-diphenolase | - |
Agaricus bisporus |
o-diphenolase | - |
Streptomyces glaucescens |
oxytyrosinase | - |
Neurospora crassa |
oxytyrosinase | - |
Agaricus bisporus |
oxytyrosinase | - |
Streptomyces glaucescens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
29.4 | - |
L-isoproterenol | - |
Agaricus bisporus | |
29.8 | - |
D-isoproterenol | - |
Agaricus bisporus | |
35.5 | - |
L-3,4-dihydroxyphenylalanine methyl ester | - |
Agaricus bisporus | |
44.3 | - |
L-2-methyl-3,4-dihydroxyphenylalanine | - |
Agaricus bisporus | |
44.3 | - |
D-2-methyl-3,4-dihydroxyphenylalanine | - |
Agaricus bisporus | |
107.4 | - |
L-Dopa | - |
Agaricus bisporus | |
107.4 | - |
D-Dopa | - |
Agaricus bisporus | |
142 | - |
3,4-Dihydroxyphenyl acetic acid | - |
Streptomyces glaucescens | |
184 | - |
D-Dopa | - |
Streptomyces glaucescens | |
340 | - |
D-Dopa | - |
Neurospora crassa | |
395 | - |
catechol | - |
Streptomyces glaucescens | |
439 | - |
dopamine | - |
Agaricus bisporus | |
533 | - |
3,4-Dihydroxyphenyl acetic acid | - |
Agaricus bisporus | |
553.5 | - |
3,4-dihydroxyphenyl propionic acid | - |
Agaricus bisporus | |
631.6 | - |
3,4-Dihydroxyphenyl acetic acid | - |
Agaricus bisporus | |
641.8 | - |
tert-butylcatechol | - |
Agaricus bisporus | |
785 | - |
chlorogenic acid | - |
Streptomyces glaucescens | |
841.6 | - |
4-methylcatechol | - |
Agaricus bisporus | |
850 | - |
3,4-Dihydroxyphenyl acetic acid | - |
Neurospora crassa | |
875 | - |
dopamine | - |
Streptomyces glaucescens | |
877.6 | - |
catechol | - |
Agaricus bisporus | |
1070 | - |
L-Dopa | - |
Neurospora crassa | |
1263 | - |
1,2,3-benzenetriol | - |
Agaricus bisporus | |
1350 | - |
dopamine | - |
Neurospora crassa | |
1445 | - |
L-Dopa | - |
Streptomyces glaucescens | |
1830 | - |
3,4-dihydroxyphenyl propionic acid | - |
Streptomyces glaucescens | |
2340 | - |
4-methylcatechol | - |
Streptomyces glaucescens | |
3320 | - |
tert-butylcatechol | - |
Streptomyces glaucescens |