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Literature summary for 1.1.99.B6 extracted from

  • Woodyer, R.D.; Li, G.; Zhao, H.; van der Donk, W.A.
    New insight into the mechanism of methyl transfer during the biosynthesis of fosfomycin (2007), Chem. Commun. (Camb. ), 4, 359-361.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
phosphonoacetaldehyde + reduced acceptor Streptomyces fradiae fomC is required for production of fosfomycin 2-hydroxyethylphosphonate + acceptor
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?

Organism

Organism UniProt Comment Textmining
Streptomyces fradiae D2SNG2
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphonoacetaldehyde + reduced acceptor fomC is required for production of fosfomycin Streptomyces fradiae 2-hydroxyethylphosphonate + acceptor
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?

Synonyms

Synonyms Comment Organism
FomC
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Streptomyces fradiae

General Information

General Information Comment Organism
malfunction complementation of fomC disrupted mutants with 2-hydroxyethylphosphonate Streptomyces fradiae