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Literature summary for 1.1.99.38 extracted from

  • Grove, T.L.; Ahlum, J.H.; Sharma, P.; Krebs, C.; Booker, S.J.
    A consensus mechanism for radical SAM-dependent dehydrogenation? BtrN contains two [4Fe-4S] clusters (2010), Biochemistry, 49, 3783-3785.
    View publication on PubMedView publication on EuropePMC
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Metals/Ions

Metals/Ions Comment Organism Structure
Iron BtrNcontains a [4Fe-4S] cluster that delivers an electron to SAM, inducing its cleavage to the common intermediate in radical SAM reactions, the 5'-deoxyadenosyl 5'-radical. BtrN contains an additional [4Fe-4S] cluster, thought to bind in contact with the substrate to facilitate loss of the second electron in the two-electron oxidation Niallia circulans

Organism

Organism UniProt Comment Textmining
Niallia circulans Q8G907
-
-

Synonyms

Synonyms Comment Organism
BtrN
-
 Niallia circulans

Cofactor

Cofactor Comment Organism Structure
Fe-S center BtrNcontains a [4Fe-4S] cluster that delivers an electron to SAM, inducing its cleavage to the common intermediate in radical SAM reactions, the 5'-deoxyadenosyl 5'-radical. BtrN contains an additional [4Fe-4S] cluster, thought to bind in contact with the substrate to facilitate loss of the second electron in the two-electron oxidation Niallia circulans