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Literature summary for 1.1.98.3 extracted from

  • Bhutani, I.; Loharch, S.; Gupta, P.; Madathil, R.; Parkesh, R.
    Structure, dynamics, and interaction of Mycobacterium tuberculosis (Mtb) DprE1 and DprE2 examined by molecular modeling, simulation, and electrostatic studies (2015), PLoS ONE, 10, e0119771.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.1.98.3

Inhibitors

Inhibitors Comment Organism Structure
BTZ043
-
 Mycobacterium tuberculosis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
trans,octacis-decaprenylphospho-beta-D-ribofuranose + FAD Mycobacterium tuberculosis
-
 trans,octacis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose + FADH2
-
 ?
trans,octacis-decaprenylphospho-beta-D-ribofuranose + FAD Mycobacterium tuberculosis H37Rv
-
 trans,octacis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose + FADH2
-
 ?
trans,octacis-decaprenylphospho-beta-D-ribofuranose + FAD Mycobacterium tuberculosis CDC 1551
-
 trans,octacis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose + FADH2
-
 ?

Organism

Organism UniProt Comment Textmining
Mycobacterium tuberculosis P9WJF0
-
-
Mycobacterium tuberculosis P9WJF1
-
-
Mycobacterium tuberculosis CDC 1551 P9WJF0
-
-
Mycobacterium tuberculosis H37Rv P9WJF1
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
trans,octacis-decaprenylphospho-beta-D-ribofuranose + FAD
-
 Mycobacterium tuberculosis trans,octacis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose + FADH2
-
 ?
trans,octacis-decaprenylphospho-beta-D-ribofuranose + FAD
-
 Mycobacterium tuberculosis H37Rv trans,octacis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose + FADH2
-
 ?
trans,octacis-decaprenylphospho-beta-D-ribofuranose + FAD
-
 Mycobacterium tuberculosis CDC 1551 trans,octacis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose + FADH2
-
 ?

Synonyms

Synonyms Comment Organism
decaprenylphosphoryl-beta-D-ribose oxidase
-
 Mycobacterium tuberculosis
DprE1
-
 Mycobacterium tuberculosis

Cofactor

Cofactor Comment Organism Structure
FAD
-
 Mycobacterium tuberculosis