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Literature summary for 1.1.5.2 extracted from

  • Oubrie, A.
    Structure and mechanism of soluble glucose dehydrogenase and other PQQ-dependent enzymes (2003), Biochim. Biophys. Acta, 1647, 143-151.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
crystal structure analysis of enzyme in ternary complex with beta-D-glucose and PQQ Acinetobacter calcoaceticus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm soluble enzyme sGDH Acinetobacter calcoaceticus 5737
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
beta-D-glucose + ubiquinone Acinetobacter calcoaceticus
-
D-glucono-1,5-lactone + ubiquinol
-
?

Organism

Organism UniProt Comment Textmining
Acinetobacter calcoaceticus
-
soluble enzyme form sGDH
-

Reaction

Reaction Comment Organism Reaction ID
D-glucose + ubiquinone = D-glucono-1,5-lactone + ubiquinol active site structure from crystal structure, and detailed catalytic mechanism Acinetobacter calcoaceticus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
beta-D-glucose + ubiquinone
-
Acinetobacter calcoaceticus D-glucono-1,5-lactone + ubiquinol
-
?
beta-D-glucose + ubiquinone redox-related structural changes, overview Acinetobacter calcoaceticus D-glucono-1,5-lactone + ubiquinol
-
?

Subunits

Subunits Comment Organism
More redox-related structural changes, overview Acinetobacter calcoaceticus

Synonyms

Synonyms Comment Organism
sGDH
-
Acinetobacter calcoaceticus
soluble glucose dehydrogenase
-
Acinetobacter calcoaceticus

Cofactor

Cofactor Comment Organism Structure
pyrroloquinoline quinone i.e. PQQ, dependent on, functions as a redox mediator by transfer of hydride ions and electrons, redox-related structural changes, overview Acinetobacter calcoaceticus