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Literature summary for 1.1.1.B40 extracted from

  • Kim, C.H.; Cho, Y.S.
    Selection and optimization of MCF-7 cell line for screening selective inhibitors of 11beta-hydroxysteroid dehydrogenase 2 (2010), Cell Biochem. Funct., 28, 440-447.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
glycyrrhetinic acid
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Caco-2 cell
-
Homo sapiens
-
MCF-7 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cortisol + NAD+
-
Homo sapiens cortisone + NADH + H+
-
?

Synonyms

Synonyms Comment Organism
11beta-hydroxysteroid dehydrogenase 2
-
Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0000024
-
cell-based assay, pH not specified in the publication, temperature not specified in the publication Homo sapiens glycyrrhetinic acid