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Literature summary for 1.1.1.85 extracted from
- Amino acid residues that determine functional specificity of NADP- and NAD-dependent isocitrate and isopropylmalate dehydrogenases (2006), Proteins, 64, 1001-1009.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview | Thermus thermophilus |
| phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview | Leptospira interrogans |
| phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview | Salmonella enterica subsp. enterica serovar Typhimurium |
| phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview | Clostridium pasteurianum |
| phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview | Bacteroides fragilis |
| phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview | Brassica napus |
| phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview | Arthrospira platensis |
| phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview | Acidithiobacillus ferrooxidans |
| phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview | Azotobacter vinelandii |
| phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview | Agrobacterium tumefaciens |
| phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview | Saccharomyces cerevisiae |
| phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview | Aspergillus niger |
| phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview | Zymoseptoria tritici |
| phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview | Eremothecium gossypii |
| phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview | Ogataea angusta |
| phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview | Cyberlindnera jadinii |
| phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview | [Candida] boidinii |
| phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview | Scheffersomyces stipitis |
| phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview | Candida maltosa |
| phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview | Escherichia coli |
| phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview | Mycobacterium tuberculosis variant bovis |
| phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview | Thermus aquaticus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Acidithiobacillus ferrooxidans | Q56268 | gene leuB | - |
| Agrobacterium tumefaciens | P24404 | gene leuB | - |
| Arthrospira platensis | Q00412 | - |
- |
| Aspergillus niger | P87256 | gene leu2A | - |
| Azotobacter vinelandii | P96197 | - |
- |
| Bacteroides fragilis | P54354 | gene leuB | - |
| Brassica napus | P29102 | - |
- |
| Candida maltosa | P07139 | gene leu2 | - |
| Clostridium pasteurianum | P31958 | - |
- |
| Cyberlindnera jadinii | P08791 | gene leu2 | - |
| Eremothecium gossypii | O60027 | i.e. Eremothecium gossypii, gene leu2 | - |
| Escherichia coli | P30125 | gene leuB | - |
| Leptospira interrogans | P24015 | gene leuB | - |
| Mycobacterium tuberculosis variant bovis | P94929 | gene leuB | - |
| Ogataea angusta | P34733 | gene leu2 | - |
| Saccharomyces cerevisiae | P87267 | orf Ydr417C | - |
| Salmonella enterica subsp. enterica serovar Typhimurium | P37412 | gene leuB | - |
| Scheffersomyces stipitis | O94114 | gene leu2 | - |
| Thermus aquaticus | P24098 | gene leuB | - |
| Thermus thermophilus | P61494 | gene leuB | - |
| Thermus thermophilus | P61495 | gene leuB | - |
| Thermus thermophilus HB27 / ATCC BAA-163 / DSM 7039 | P61494 | gene leuB | - |
| Zymoseptoria tritici | Q9Y897 | i.e. Septoria tritici, gene leuC | - |
| [Candida] boidinii | Q01987 | gene leu2 | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | substrate specificity-determining residues, e.g. L103, T105, A337, and T341, overview | Escherichia coli | ? | - |
? |  |
| additional information | substrate specificity-determining residues, overview | Thermus thermophilus | ? | - |
? | |
| additional information | substrate specificity-determining residues, overview | Leptospira interrogans | ? | - |
? | |
| additional information | substrate specificity-determining residues, overview | Salmonella enterica subsp. enterica serovar Typhimurium | ? | - |
? | |
| additional information | substrate specificity-determining residues, overview | Clostridium pasteurianum | ? | - |
? | |
| additional information | substrate specificity-determining residues, overview | Bacteroides fragilis | ? | - |
? | |
| additional information | substrate specificity-determining residues, overview | Brassica napus | ? | - |
? | |
| additional information | substrate specificity-determining residues, overview | Arthrospira platensis | ? | - |
? | |
| additional information | substrate specificity-determining residues, overview | Acidithiobacillus ferrooxidans | ? | - |
? | |
| additional information | substrate specificity-determining residues, overview | Azotobacter vinelandii | ? | - |
? | |
| additional information | substrate specificity-determining residues, overview | Agrobacterium tumefaciens | ? | - |
? | |
| additional information | substrate specificity-determining residues, overview | Saccharomyces cerevisiae | ? | - |
? | |
| additional information | substrate specificity-determining residues, overview | Aspergillus niger | ? | - |
? | |
| additional information | substrate specificity-determining residues, overview | Zymoseptoria tritici | ? | - |
? | |
| additional information | substrate specificity-determining residues, overview | Eremothecium gossypii | ? | - |
? | |
| additional information | substrate specificity-determining residues, overview | Ogataea angusta | ? | - |
? | |
| additional information | substrate specificity-determining residues, overview | Cyberlindnera jadinii | ? | - |
? | |
| additional information | substrate specificity-determining residues, overview | [Candida] boidinii | ? | - |
? | |
| additional information | substrate specificity-determining residues, overview | Scheffersomyces stipitis | ? | - |
? | |
| additional information | substrate specificity-determining residues, overview | Candida maltosa | ? | - |
? | |
| additional information | substrate specificity-determining residues, overview | Mycobacterium tuberculosis variant bovis | ? | - |
? | |
| additional information | substrate specificity-determining residues, overview | Thermus aquaticus | ? | - |
? | |
| additional information | substrate specificity-determining residues, overview | Thermus thermophilus HB27 / ATCC BAA-163 / DSM 7039 | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| More | three-dimensional structure comparison, overview | Escherichia coli |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| IMDH | - |
Thermus thermophilus |
| IMDH | - |
Leptospira interrogans |
| IMDH | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
| IMDH | - |
Clostridium pasteurianum |
| IMDH | - |
Bacteroides fragilis |
| IMDH | - |
Brassica napus |
| IMDH | - |
Arthrospira platensis |
| IMDH | - |
Acidithiobacillus ferrooxidans |
| IMDH | - |
Azotobacter vinelandii |
| IMDH | - |
Agrobacterium tumefaciens |
| IMDH | - |
Saccharomyces cerevisiae |
| IMDH | - |
Aspergillus niger |
| IMDH | - |
Zymoseptoria tritici |
| IMDH | - |
Eremothecium gossypii |
| IMDH | - |
Ogataea angusta |
| IMDH | - |
Cyberlindnera jadinii |
| IMDH | - |
[Candida] boidinii |
| IMDH | - |
Scheffersomyces stipitis |
| IMDH | - |
Candida maltosa |
| IMDH | - |
Escherichia coli |
| IMDH | - |
Mycobacterium tuberculosis variant bovis |
| IMDH | - |
Thermus aquaticus |
| NAD-dependent isopropylmalate dehydrogenase | - |
Thermus thermophilus |
| NAD-dependent isopropylmalate dehydrogenase | - |
Leptospira interrogans |
| NAD-dependent isopropylmalate dehydrogenase | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
| NAD-dependent isopropylmalate dehydrogenase | - |
Clostridium pasteurianum |
| NAD-dependent isopropylmalate dehydrogenase | - |
Bacteroides fragilis |
| NAD-dependent isopropylmalate dehydrogenase | - |
Brassica napus |
| NAD-dependent isopropylmalate dehydrogenase | - |
Arthrospira platensis |
| NAD-dependent isopropylmalate dehydrogenase | - |
Acidithiobacillus ferrooxidans |
| NAD-dependent isopropylmalate dehydrogenase | - |
Azotobacter vinelandii |
| NAD-dependent isopropylmalate dehydrogenase | - |
Agrobacterium tumefaciens |
| NAD-dependent isopropylmalate dehydrogenase | - |
Saccharomyces cerevisiae |
| NAD-dependent isopropylmalate dehydrogenase | - |
Aspergillus niger |
| NAD-dependent isopropylmalate dehydrogenase | - |
Zymoseptoria tritici |
| NAD-dependent isopropylmalate dehydrogenase | - |
Eremothecium gossypii |
| NAD-dependent isopropylmalate dehydrogenase | - |
Ogataea angusta |
| NAD-dependent isopropylmalate dehydrogenase | - |
Cyberlindnera jadinii |
| NAD-dependent isopropylmalate dehydrogenase | - |
[Candida] boidinii |
| NAD-dependent isopropylmalate dehydrogenase | - |
Scheffersomyces stipitis |
| NAD-dependent isopropylmalate dehydrogenase | - |
Candida maltosa |
| NAD-dependent isopropylmalate dehydrogenase | - |
Escherichia coli |
| NAD-dependent isopropylmalate dehydrogenase | - |
Mycobacterium tuberculosis variant bovis |
| NAD-dependent isopropylmalate dehydrogenase | - |
Thermus aquaticus |
| Ydr417cp | - |
Saccharomyces cerevisiae |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | dependent on, cofactor specificity-determining residues, overview | Thermus thermophilus | |
| NAD+ | dependent on, cofactor specificity-determining residues, overview | Leptospira interrogans | |
| NAD+ | dependent on, cofactor specificity-determining residues, overview | Salmonella enterica subsp. enterica serovar Typhimurium | |
| NAD+ | dependent on, cofactor specificity-determining residues, overview | Clostridium pasteurianum | |
| NAD+ | dependent on, cofactor specificity-determining residues, overview | Bacteroides fragilis | |
| NAD+ | dependent on, cofactor specificity-determining residues, overview | Brassica napus | |
| NAD+ | dependent on, cofactor specificity-determining residues, overview | Arthrospira platensis | |
| NAD+ | dependent on, cofactor specificity-determining residues, overview | Acidithiobacillus ferrooxidans | |
| NAD+ | dependent on, cofactor specificity-determining residues, overview | Azotobacter vinelandii | |
| NAD+ | dependent on, cofactor specificity-determining residues, overview | Agrobacterium tumefaciens | |
| NAD+ | dependent on, cofactor specificity-determining residues, overview | Saccharomyces cerevisiae | |
| NAD+ | dependent on, cofactor specificity-determining residues, overview | Aspergillus niger | |
| NAD+ | dependent on, cofactor specificity-determining residues, overview | Zymoseptoria tritici | |
| NAD+ | dependent on, cofactor specificity-determining residues, overview | Eremothecium gossypii | |
| NAD+ | dependent on, cofactor specificity-determining residues, overview | Ogataea angusta | |
| NAD+ | dependent on, cofactor specificity-determining residues, overview | Cyberlindnera jadinii | |
| NAD+ | dependent on, cofactor specificity-determining residues, overview | [Candida] boidinii | |
| NAD+ | dependent on, cofactor specificity-determining residues, overview | Scheffersomyces stipitis | |
| NAD+ | dependent on, cofactor specificity-determining residues, overview | Candida maltosa | |
| NAD+ | dependent on, cofactor specificity-determining residues, overview | Escherichia coli | |
| NAD+ | dependent on, cofactor specificity-determining residues, overview | Mycobacterium tuberculosis variant bovis | |
| NAD+ | dependent on, cofactor specificity-determining residues, overview | Thermus aquaticus | |
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