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Literature summary for 1.1.1.85 extracted from

  • Wallon, G.; Kryger, G.; Lovett, S.T.; Oshima, T.; Ringe, D.; Petsko, G.A.
    Crystal structures of Escherichia coli and Salmonella typhimurium 3-isopropylmalate dehydrogenase and comparison with their thermophilic counterpart from Thermus thermophilus (1997), J. Mol. Biol., 266, 1016-1031.
    View publication on PubMed
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Crystallization (Commentary)

Crystallization (Comment) Organism
crystal structures of Escherichia coli and Salmonella typhimurium 3-isopropylmalate dehydrogenase and comparison with their thermophilic counterpart from Thermus thermophilus Salmonella enterica subsp. enterica serovar Typhimurium
crystal structures of Escherichia coli and Salmonella typhimurium 3-isopropylmalate dehydrogenase and comparison with their thermophilic counterpart from Thermus thermophilus Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-
Thermus thermophilus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(2R,3S)-3-isopropylmalate + NAD+
-
 Salmonella enterica subsp. enterica serovar Typhimurium 2-oxoisocaproate + NADH + H+ + CO2
-
 ?
(2R,3S)-3-isopropylmalate + NAD+
-
 Thermus thermophilus 2-oxoisocaproate + NADH + H+ + CO2
-
 ?
(2R,3S)-3-isopropylmalate + NAD+
-
 Escherichia coli 2-oxoisocaproate + NADH + H+ + CO2
-
 ?

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Salmonella enterica subsp. enterica serovar Typhimurium
NAD+
-
 Thermus thermophilus
NAD+
-
 Escherichia coli