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Literature summary for 1.1.1.8 extracted from

  • Valadi, A.; Granath, K.; Gustafsson, L.; Adler, L.
    Distinct intracellular localization of Gpd1p and Gpd2p, the two yeast isoforms of NAD+-dependent glycerol-3-phosphate dehydrogenase, explains their different contributions to redox-driven glycerol production (2004), J. Biol. Chem., 279, 39677-39685.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
Deltagpd1 anaerobic growth, growth rate and glycerol production similar to wild-type Saccharomyces cerevisiae
Deltagpd1/Deltacox18 anaerobic growth, growth rate and glycerol production similar to wild-type Saccharomyces cerevisiae
Deltagpd2 50% decrease in anaerobic glycerol production Saccharomyces cerevisiae
Deltagpd2/Deltacox18 no growth under anaerobic or aerobic conditions Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol isoform Gpd2p, partly isoform Gpd1p Saccharomyces cerevisiae 5829
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mitochondrion isoform Gpd2p, contains mitochondrial presequence sufficient for targeting Saccharomyces cerevisiae 5739
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peroxisome isoform Gdp1p, partly Saccharomyces cerevisiae 5777
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Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
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isoforms Gdp1p, Gdp2p
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