Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endoplasmic reticulum | - |
Danio rerio | 5783 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Danio rerio | - |
- |
- |
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | low activity in both sexes | Danio rerio | - |
embryo | during embryogenesis the enzyme is present from the sphere stage until hatching | Danio rerio | - |
eye | - |
Danio rerio | - |
heart | expression in male, hardly detectable in female | Danio rerio | - |
intestine | expression in male, hardly detectable in female | Danio rerio | - |
kidney | expression in male, hardly detectable in female | Danio rerio | - |
liver | - |
Danio rerio | - |
muscle | - |
Danio rerio | - |
skin | expression in male, hardly detectable in female | Danio rerio | - |
spleen | expression in male, hardly detectable in female | Danio rerio | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
11-hydroxy-androstenedione + NADPH | - |
Homo sapiens | 11beta-hydroxy-testosterone | - |
? | |
11-hydroxy-androstenedione + NADPH | - |
Danio rerio | 11beta-hydroxy-testosterone | - |
? | |
11-ketoandrostenedione + NADPH | - |
Homo sapiens | 11-ketotestosterone + NADP+ | - |
? | |
11-ketoandrostenedione + NADPH | - |
Danio rerio | 11-ketotestosterone + NADP+ | - |
? | |
androstanedione + NADPH | - |
Homo sapiens | dihydrotestosterone + NADP+ | - |
? | |
androstenedione + NADPH + H+ | - |
Homo sapiens | testosterone + NADP+ | - |
r | |
androstenedione + NADPH + H+ | - |
Danio rerio | testosterone + NADP+ | - |
r | |
androsterone + NADPH + H+ | - |
Homo sapiens | androstane-3beta,17beta-diol + NADP+ | - |
? | |
dehydroepiandrosterone + NADPH | - |
Homo sapiens | androst-5-en-3beta,17beta-diol + NADP+ | - |
? | |
dehydroepiandrosterone + NADPH | - |
Danio rerio | androst-5-en-3beta,17beta-diol + NADP+ | - |
? | |
epiandrosterone + NADPH | - |
Homo sapiens | androstane-3beta,17beta-diol + NADP+ | - |
? | |
epiandrosterone + NADPH | - |
Danio rerio | androstane-3beta,17beta-diol + NADP+ | - |
? | |
testosterone + NAD+ | NAD+ shows 20% of the activity with NADP+ | Homo sapiens | androstenedione + NADH | - |
ir | |
testosterone + NAD+ | NAD+ shows ess than 10% of the activity with NADP+ | Danio rerio | androstenedione + NADH | - |
ir |
Synonyms | Comment | Organism |
---|---|---|
17beta-HSD 3 | - |
Homo sapiens |
17beta-HSD 3 | - |
Danio rerio |
17beta-hydroxysteroid dehydrogenase type 3 | - |
Homo sapiens |
17beta-hydroxysteroid dehydrogenase type 3 | - |
Danio rerio |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | 20% of the activity with NADP+, cosubstrate: testosterone | Homo sapiens | |
NAD+ | less than 10% of the activity with NADP+, cosubstrate: testosterone | Danio rerio | |
NADP+ | - |
Homo sapiens | |
NADP+ | - |
Danio rerio | |
NADPH | no activity with NADH | Homo sapiens | |
NADPH | no activity with NADH | Danio rerio |