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Literature summary for 1.1.1.62 extracted from

  • Sivik, T.; Gunnarsson, C.; Fornander, T.; Nordenskjoeld, B.; Skoog, L.; Stal, O.; Jansson, A.
    17beta-Hydroxysteroid dehydrogenase type 14 is a predictive marker for tamoxifen response in oestrogen receptor positive breast cancer (2012), PLoS ONE, 7, e40568.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine Patients with oestrogen positive tumours with high isoform 17betaHSD14 expression have fewer local recurrences when treated with tamoxifen compared to patients with lower tumoural 17betaHSD14 expression, for whom tamoxifen does not reduce the number of local recurrences. No prognostic importance of 17betaHSD14 is seen for systemically untreated patients Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9BPX1
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-

Source Tissue

Source Tissue Comment Organism Textmining
breast cancer cell
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Homo sapiens
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Synonyms

Synonyms Comment Organism
17betaHSD14
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Homo sapiens