Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(16alpa,17beta)-16-(3-bromopropyl)estra-1(10),2,4-triene-3,17-diol | EM-251 | Homo sapiens | |
(3-amino-5-[13-[(16beta,17beta)-3,17-dihydroxyestra-1(10),2,4-trien-16-yl]tridecyl]phenyl)acetic acid | - |
Homo sapiens | |
(3-[(4-aminophenyl)carbonyl]-5-[13-[(16beta,17beta)-3,17-dihydroxyestra-1(10),2,4-trien-16-yl]tridecyl]phenyl)acetic acid | - |
Homo sapiens | |
(3-[13-[(16beta,17beta)-3,17-dihydroxyestra-1(10),2,4-trien-16-yl]tridecyl]phenyl)acetic acid | - |
Homo sapiens | |
5'-O-[9-[(16beta,17beta)-3,17-dihydroxyestra-1(10),2,4-trien-16-yl]nonanoyl]adenosine | EM-1745, bisubstrate inhibitor of 17beta-HSD1 | Homo sapiens | |
EM-1745 | bisubstrate inhibitor of 17beta-HSD1 | Homo sapiens | |
N-butyl-6-[[(6beta,17beta)-3,17-dihydroxyestra-1(10),2,4-trien-6-yl]oxy]-N-methylhexanamide | - |
Homo sapiens | |
N-butyl-6-[[(6beta,17beta)-3,17-dihydroxyestra-1(10),2,4-trien-6-yl]sulfanyl]-N-methylhexanamide | EM-678 | Homo sapiens | |
N-butyl-7-[(6beta,17beta)-3,17-dihydroxyestra-1(10),2,4-trien-6-yl]-N-methylheptanamide | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P14061 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dehydroepiandrosterone + NAD(P)H | - |
Homo sapiens | androst-5-ene-3beta,17beta-diol + NAD(P)+ | - |
? | |
estradiol-17beta + NAD(P)+ | - |
Homo sapiens | estrone + NAD(P)H + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
17beta-HSD1 | - |
Homo sapiens |
type 1 17beta-hydroxysteroid dehydrogenase | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD(P)+ | - |
Homo sapiens |