Application | Comment | Organism |
---|---|---|
medicine | disease iondications for HSD17B1 inhibitors in disorders in the female reproductive organs associated with enhanced androgen action, such as ovarian serous cystadenomas | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
transgenic mouse lines universally overexpressing human HSD17B1 are generated and characterized at fetal and adult ages | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
androstenedione + NAD(P)H + H+ | Homo sapiens | - |
testosterone + NADP+ | - |
? | |
estrone + NAD(P)H + H+ | Homo sapiens | - |
estradiol + NAD(P)+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P14016 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
androstenedione + NAD(P)H + H+ | - |
Homo sapiens | testosterone + NADP+ | - |
? | |
estrone + NAD(P)H + H+ | - |
Homo sapiens | estradiol + NAD(P)+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
HSD17B1 | - |
Homo sapiens |