Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli M15 cells | Ovis aries |
Protein Variants | Comment | Organism |
---|---|---|
E131A | the mutant shows a 2.3fold decrease in turnover number compared to the wild type enzyme | Ovis aries |
M13C | the mutant shows a decrease in turnover number compared to the wild type enzyme | Ovis aries |
M13Q | the mutant shows a 8.1fold decrease in turnover number compared to the wild type enzyme | Ovis aries |
M13V | the mutant shows a decrease in turnover number compared to the wild type enzyme | Ovis aries |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Ovis aries | - |
- |
- |
Purification (Comment) | Organism |
---|---|
Ni-NTA column chromatography and ADP-agarose column chromatography | Ovis aries |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Ovis aries | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-deoxy-6-phospho-D-gluconate + NADP+ | - |
Ovis aries | 3-oxo-2-deoxy-6-phosphogluconate + NADPH | - |
? | |
6-phospho-D-gluconate + NADP+ | - |
Ovis aries | D-ribulose 5-phosphate + CO2 + NADPH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
6-phosphogluconate dehydrogenase | - |
Ovis aries |
6PGDH | - |
Ovis aries |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Ovis aries |