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Literature summary for 1.1.1.44 extracted from
- Crystalline 6-phosphogluconate dehydrogenase from sheep liver (1973), Eur. J. Biochem., 38, 229-238.
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
- |
Cyberlindnera jadinii |
- |
Ovis aries |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 5,5'-dithiobis(2-nitrobenzoic acid) | - |
Cyberlindnera jadinii |  |
| 5,5'-dithiobis(2-nitrobenzoic acid) | - |
Ovis aries | |
| p-hydroxymercuribenzoate | - |
Ovis aries | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 47000 | - |
2 * 47000, SDS-PAGE | Ovis aries |
| 90000 | - |
gel filtration, Bio-Gel 200 | Ovis aries |
| 92000 | - |
gel filtration, PAGE | Ovis aries |
| 94000 | - |
gel filtration, in presence of MgCl2 | Ovis aries |
| 95000 | - |
gel filtration | Ovis aries |
| 98000 | - |
sedimentation equilibrium | Ovis aries |
| 101000 | - |
gel filtration | Cyberlindnera jadinii |
| 102000 | - |
gel filtration | Rattus norvegicus |
| 129000 | - |
sedimentation equilibrium, short column method | Ovis aries |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 6-phospho-D-gluconate + NADP+ | Cyberlindnera jadinii | - |
D-ribulose 5-phosphate + CO2 + NADPH + H+ | - |
r | |
| 6-phospho-D-gluconate + NADP+ | Rattus norvegicus | - |
D-ribulose 5-phosphate + CO2 + NADPH + H+ | - |
r | |
| 6-phospho-D-gluconate + NADP+ | Ovis aries | - |
D-ribulose 5-phosphate + CO2 + NADPH + H+ | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Cyberlindnera jadinii | - |
- |
- |
| Ovis aries | - |
sheep | - |
| Rattus norvegicus | - |
rat | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
- |
Ovis aries |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
| liver | - |
Ovis aries | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 21.2 | - |
- |
Ovis aries |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 6-phospho-D-gluconate + NADP+ | - |
Cyberlindnera jadinii | D-ribulose 5-phosphate + CO2 + NADPH + H+ | - |
r | |
| 6-phospho-D-gluconate + NADP+ | - |
Rattus norvegicus | D-ribulose 5-phosphate + CO2 + NADPH + H+ | - |
r | |
| 6-phospho-D-gluconate + NADP+ | - |
Ovis aries | D-ribulose 5-phosphate + CO2 + NADPH + H+ | - |
r | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | - |
Cyberlindnera jadinii |
| dimer | - |
Rattus norvegicus |
| dimer | 2 * 47000, SDS-PAGE | Ovis aries |
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Release 2023.1 (January 2023)
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