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Literature summary for 1.1.1.397 extracted from

  • Du, Y.; Alkhalaf, L.; Ryan, K.
    In vitro reconstitution of indolmycin biosynthesis reveals the molecular basis of oxazolinone assembly (2015), Proc. Natl. Acad. Sci. USA, 112, 2717-2722.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.1.1.397

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BW25113 cells Streptomyces griseus subsp. griseus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(2S,3R)-2-hydroxy-3-(indol-3-yl)butanoate + NAD+ Streptomyces griseus subsp. griseus
-
 (R)-3-(indol-3-yl)-2-oxobutanoate + NADH + H+
-
 ?
(2S,3R)-2-hydroxy-3-(indol-3-yl)butanoate + NAD+ Streptomyces griseus subsp. griseus ATCC 12648
-
 (R)-3-(indol-3-yl)-2-oxobutanoate + NADH + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Streptomyces griseus subsp. griseus A0A0D4BSN8
-
-
Streptomyces griseus subsp. griseus ATCC 12648 A0A0D4BSN8
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(2S,3R)-2-hydroxy-3-(indol-3-yl)butanoate + NAD+
-
 Streptomyces griseus subsp. griseus (R)-3-(indol-3-yl)-2-oxobutanoate + NADH + H+
-
 ?
(2S,3R)-2-hydroxy-3-(indol-3-yl)butanoate + NAD+
-
 Streptomyces griseus subsp. griseus ATCC 12648 (R)-3-(indol-3-yl)-2-oxobutanoate + NADH + H+
-
 ?

Synonyms

Synonyms Comment Organism
ind2
-
 Streptomyces griseus subsp. griseus