Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ATP | 70-85% residual activity at 10 mM | Methylobacillus flagellatus | |
D-ribulose 5-phosphate | 60% residual activity at 2 mM | Methylobacillus flagellatus | |
NADH | 30-40% residual activity at 0.2 mM, the enzyme is inhibited by NADH and NADPH to a similar extend | Methylobacillus flagellatus | |
NADPH | 25-35% residual activity at 0.2 mM, the enzyme is inhibited by NADH and NADPH to a similar extend | Methylobacillus flagellatus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Methylobacillus flagellatus | - |
- |
- |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.07 | - |
with NADP+ as cosubstrate, at 30°C and pH 8.0 | Methylobacillus flagellatus |
0.67 | - |
with NAD+ as cosubstrate, at 30°C and pH 8.0 | Methylobacillus flagellatus |
Storage Stability | Organism |
---|---|
4°C, 30 days, no loss of activity | Methylobacillus flagellatus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
6-phospho-D-gluconate + NADP+ | - |
Methylobacillus flagellatus | D-ribulose 5-phosphate + CO2 + NADPH + H+ | - |
? | |
6-phospho-D-gluconate + NADP+ | - |
Methylobacillus flagellatus KT1 | D-ribulose 5-phosphate + CO2 + NADPH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
6-phosphogluconate dehydrogenase | - |
Methylobacillus flagellatus |
gnd | - |
Methylobacillus flagellatus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | the enzyme is specific to both to NAD+ and NADP+ | Methylobacillus flagellatus | |
NADP+ | the enzyme is specific to both to NAD+ and NADP+ | Methylobacillus flagellatus |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Methylobacillus flagellatus | isoelectric focusing | - |
6.5 |