Organism | UniProt | Comment | Textmining |
---|---|---|---|
Methanocaldococcus jannaschii | Q58820 | - |
- |
Methanothermus fervidus | P16142 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-oxoglutarate + NADH + H+ | - |
Methanocaldococcus jannaschii | (S)-2-hydroxyglutarate + NAD+ | - |
? | |
additional information | enzyme catalyzes the NADH-dependent reduction of oxaloacetate, 2-oxoglutarate, and pyruvate to the corresponding (S)-2-hydroxyacids with pro-S NADH-stereospecificity | Methanocaldococcus jannaschii | ? | - |
? | |
oxaloacetate + NADH + H+ | transfer of pro-4S hydrogen from the reduced coenzyme to the 2-oxoacid substrate | Methanocaldococcus jannaschii | (S)-malate + NAD+ | - |
? | |
oxaloacetate + NADH + H+ | transfer of pro-4S hydrogen from the reduced coenzyme to the 2-oxoacid substrate | Methanothermus fervidus | (S)-malate + NAD+ | - |
? | |
pyruvate + NADH + H+ | - |
Methanocaldococcus jannaschii | (S)-lactate + NAD+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MDH I | - |
Methanocaldococcus jannaschii |
MDH I | - |
Methanothermus fervidus |
MJ1425 | - |
Methanocaldococcus jannaschii |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | - |
Methanothermus fervidus |