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Literature summary for 1.1.1.30 extracted from

  • Cortese, J.D.; Fleischer, S.
    Noncooperative vs. cooperative reactivation of D-beta-hydroxybutyrate dehydrogenase: multiple equilibria for lecithin binding are determined by the physical state (soluble vs. bilayer) and composition of the phospholipids (1987), Biochemistry, 26, 5283-5293.
    View publication on PubMed
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Activating Compound

Activating Compound Comment Organism Structure
phosphatidylcholine state of phosphatidylcholine determines nature of activation, noncooperative for soluble phosphatidylcholine, cooperative for bilayer phosphatidylcholine Rattus norvegicus
phosphatidylcholine state of phosphatidylcholine determines nature of activation, noncooperative for soluble phosphatidylcholine, cooperative for bilayer phosphatidylcholine Bos taurus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Rattus norvegicus 5739
-
mitochondrion
-
 Bos taurus 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(R)-3-hydroxybutanoate + NAD+ Rattus norvegicus
-
 acetoacetate + NADH
-
 r
(R)-3-hydroxybutanoate + NAD+ Bos taurus
-
 acetoacetate + NADH
-
 r

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Rattus norvegicus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(R)-3-hydroxybutanoate + NAD+
-
 Rattus norvegicus acetoacetate + NADH
-
 r
(R)-3-hydroxybutanoate + NAD+
-
 Bos taurus acetoacetate + NADH
-
 r

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Rattus norvegicus
NAD+
-
 Bos taurus