Protein Variants | Comment | Organism |
---|---|---|
D259N | 56fold reduction in kcat, 5fold lowering of Km, shifting of the enzymatic activity profile towards the acidic range by two units | Lactobacillus delbrueckii subsp. bulgaricus |
H205K | 125-fold reduction in Kcat | Lactobacillus delbrueckii subsp. bulgaricus |
H296K | no significant change | Lactobacillus delbrueckii subsp. bulgaricus |
H303K | Km for pyruvate increased fourfold | Lactobacillus delbrueckii subsp. bulgaricus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(R)-lactate + NAD+ | Lactobacillus delbrueckii subsp. bulgaricus | - |
pyruvate + NADH | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Lactobacillus delbrueckii subsp. bulgaricus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(R)-lactate + NAD+ | - |
Lactobacillus delbrueckii subsp. bulgaricus | pyruvate + NADH | - |
? |