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Literature summary for 1.1.1.258 extracted from

  • Donoghue, N.A.; Trudgill, P.W.
    The metabolism of cyclohexanol by Acinetobacter NCIB 9871 (1975), Eur. J. Biochem., 60, 1-7.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6-hydroxyhexanoate + NAD+ Nocardia globerula
-
6-oxohexanoate + NADH
-
r
6-hydroxyhexanoate + NAD+ Acinetobacter sp. involved in the degradation pathway from cyclohexanol to adipate 6-oxohexanoate + NADH
-
r
6-hydroxyhexanoate + NAD+ Acinetobacter sp. NCIB 9871 involved in the degradation pathway from cyclohexanol to adipate 6-oxohexanoate + NADH
-
r
6-hydroxyhexanoate + NAD+ Nocardia globerula CL1
-
6-oxohexanoate + NADH
-
r

Organism

Organism UniProt Comment Textmining
Acinetobacter sp.
-
-
-
Acinetobacter sp. NCIB 9871
-
-
-
Nocardia globerula
-
-
-
Nocardia globerula CL1
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
culture condition:cyclohexanol-grown cell induction of enzyme synthesis by growth in cyclohexanol containing medium Acinetobacter sp.
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.03
-
-
Acinetobacter sp.

Storage Stability

Storage Stability Organism
very labile to storage Acinetobacter sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6-hydroxyhexanoate + NAD+
-
Nocardia globerula 6-oxohexanoate + NADH
-
r
6-hydroxyhexanoate + NAD+ involved in the degradation pathway from cyclohexanol to adipate Acinetobacter sp. 6-oxohexanoate + NADH
-
r
6-hydroxyhexanoate + NAD+ involved in the degradation pathway from cyclohexanol to adipate Acinetobacter sp. NCIB 9871 6-oxohexanoate + NADH
-
r
6-hydroxyhexanoate + NAD+
-
Nocardia globerula CL1 6-oxohexanoate + NADH
-
r

Cofactor

Cofactor Comment Organism Structure
NAD+ can not be replaced by NADP+ Acinetobacter sp.