Literature summary for 1.1.1.247 extracted from

Larkin, P.J.; Miller, J.A.; Allen, R.S.; Chitty, J.A.; Gerlach, W.L.; Frick, S.; Kutchan, T.M.; Fist, A.J.
Increasing morphinan alkaloid production by over-expressing codeinone reductase in transgenic Papaver somniferum (2007), Plant Biotechnol. J., 5, 26-37.

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Cloned(Commentary)

Cloned (Comment)	Organism
overexpression of the enzyme in transgenic Papaver somnniferum plants leading to increased enzyme content and capsule alkaloid, morphine and total alkaloid, content without significant alterations of the alkaloid profile, overview	Papaver somniferum

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
Codeinone + NADPH	Papaver somniferum	penultimate step in morphine biosynthesis	Codeine + NADP+	-	r

Organism

Organism	UniProt	Comment	Textmining
Papaver somniferum	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
plant capsule	-	Papaver somniferum	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Codeinone + NADPH	-	Papaver somniferum	Codeine + NADP+	-	r
Codeinone + NADPH	penultimate step in morphine biosynthesis	Papaver somniferum	Codeine + NADP+	-	r

Synonyms

Synonyms	Comment	Organism
codeinone reductase	-	Papaver somniferum
PsCor1.1	-	Papaver somniferum

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Release 2023.1 (January 2023)