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Literature summary for 1.1.1.219 extracted from

  • Trabelsi, N.; Petit, P.; Manigand, C.; Langlois d'Estaintot, B.; Granier, T.; Chaudiere, J.; Gallois, B.
    Structural evidence for the inhibition of grape dihydroflavonol 4-reductase by flavonols (2008), Acta Crystallogr. Sect. D, 64, 883-891.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
DFR-NADP+-flavonol (myricetin and quercetin) complexes, at room temperature, by hanging-drop vapour diffusion method. Complex DFR-NADP+-myricetin belongs to space group P21 (unit-cell parameters a = 47.23, b = 177.96, c = 92.60 A, beta = 104.8°). Complex DFR-NADP+-quercetin belongs to space group P6122 (unit-cell parameters a = b = 174.94, c = 290.18 A) Vitis vinifera

Inhibitors

Inhibitors Comment Organism Structure
myricetin flavonol that can be an inhibitor of the activity of DFR towards dihydroflavonols Vitis vinifera
quercetin flavonol that can be an inhibitor of the activity of DFR towards dihydroflavonols Vitis vinifera

Organism

Organism UniProt Comment Textmining
Vitis vinifera
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dihydroquercetin + NADPH + H+
-
Vitis vinifera leucocyanidin + NADP+
-
?

Synonyms

Synonyms Comment Organism
DFR
-
Vitis vinifera
dihydroflavonol 4-reductase
-
Vitis vinifera

Cofactor

Cofactor Comment Organism Structure
NADP+
-
Vitis vinifera