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Literature summary for 1.1.1.213 extracted from

  • Sinreih, M.; Sosic, I.; Beranic, N.; Turk, S.; Adeniji, A.O.; Penning, T.M.; Rizner, T.L.; Gobec, S.
    N-Benzoyl anthranilic acid derivatives as selective inhibitors of aldo-keto reductase AKR1C3 (2012), Bioorg. Med. Chem. Lett., 22, 5948-5951.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
2-[[(3-hydroxyphenyl)carbonyl]amino]-4,5-dimethoxybenzoic acid
-
Homo sapiens
2-[[(3-hydroxyphenyl)carbonyl]amino]-5-nitrobenzoic acid
-
Homo sapiens
5-bromo-2-[[(3-hydroxyphenyl)carbonyl]amino]benzoic acid
-
Homo sapiens
5-chloro-2-[[(3-hydroxyphenyl)carbonyl]amino]benzoic acid
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P42330
-
-

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00084
-
pH 7.0, temperature not specified in the publication Homo sapiens 2-[[(3-hydroxyphenyl)carbonyl]amino]-5-nitrobenzoic acid
0.0019
-
pH 7.0, temperature not specified in the publication Homo sapiens 5-bromo-2-[[(3-hydroxyphenyl)carbonyl]amino]benzoic acid
0.0022
-
pH 7.0, temperature not specified in the publication Homo sapiens 5-chloro-2-[[(3-hydroxyphenyl)carbonyl]amino]benzoic acid
0.0052
-
pH 7.0, temperature not specified in the publication Homo sapiens 2-[[(3-hydroxyphenyl)carbonyl]amino]-4,5-dimethoxybenzoic acid