Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-[5-fluoro-2-methyl-1-p-(methylsulphinyl)benzylidine]indene-3-acetic acid | non-competitive | Bos taurus | |
disodium 4,6-dioxo-10-propyl-4H,6H-pyranol[3,2-g-]-quinoline-2,8-dicarboxylate | non-competitive | Bos taurus | |
glyceraldehyde | substrate inhibition | Bos taurus | |
malondialdehyde | at concentration above 0.8 mM substrate inhibition | Bos taurus | |
NADP+ | competitve to NADPH | Bos taurus | |
p-nitrobenzaldehyde | at concentration above 2 mM substrate inhibition | Bos taurus | |
sorbitol | competitive inhibition with NADP+ and glucose | Bos taurus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
8.2 | - |
NADPH | - |
Bos taurus | |
21.8 | - |
glucose | - |
Bos taurus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
32000 | - |
gel filtration | Bos taurus |
40000 | - |
1 * 40000, about, SDS-PAGE | Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
aldose + NAD(P)H | Bos taurus | - |
alditol + NAD(P)+ | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lens | - |
Bos taurus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.2 | - |
purified enzyme | Bos taurus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
alditol + NAD(P)+ | - |
Bos taurus | aldose + NAD(P)H | - |
r | |
aldose + NAD(P)H | - |
Bos taurus | alditol + NAD(P)+ | - |
r | |
D-fructose + NAD(P)H + H+ | - |
Bos taurus | D-arabino-hexitol + NAD(P)+ | - |
r | |
D-glucose + NAD(P)H | - |
Bos taurus | sorbitol + NAD(P)+ | - |
? | |
D-xylose + NAD(P)H | - |
Bos taurus | xylitol + NAD(P)+ | - |
r | |
DL-glyceraldehyde + NAD(P)H | - |
Bos taurus | glycerol + NAD(P)+ | - |
r | |
xylitol + NAD(P)+ | - |
Bos taurus | D-xylose + NAD(P)H + H+ | - |
r |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 40000, about, SDS-PAGE | Bos taurus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
additional information | - |
inactive below pH 5.9 | Bos taurus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | - |
Bos taurus | |
NADP+ | - |
Bos taurus |