Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | Q6P9U9 | IMPDH2 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
retina | inosine monophosphate dehydrogenase is present in all immature cells throughout the retina during embryonic and neonatal development. Following eye opening and cell differentiation, its distribution is restricted to the photoreceptors and bipolar cell, becoming prominent in Muller cells with ageing. Type I enzyme does not play a role in early retinal development but type Igamma has greater activity after postnatal day 10. All forms of type I show an increased propensity to form intracellular macrostructures compared to type II | Rattus norvegicus | - |