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Literature summary for 1.1.1.19 extracted from

  • Barski, O.A.; Papusha, V.Z.; Ivanova, M.M.; Rudman, D.M.; Finegold, M.J.
    Developmental expression and function of aldehyde reductase in proximal tubules of the kidney (2005), Am. J. Physiol. Renal Physiol., 289, F200-F207.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
AL-1567
-
Homo sapiens
AL-1567
-
Mus musculus

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
intestine low activity Mus musculus
-
kidney high activity. Expression is limited to the proximal tubules and parietal epithelium of Bowman's capsule. the intensity of staining increases with age Mus musculus
-
kidney high activity. Expression is limited to the proximal tubules. Enzyme is present in the 9 week old fetal kidney Homo sapiens
-
liver low activity Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-glucuronate + NADPH + H+
-
Mus musculus L-gulonate + NADP+
-
?
D-glucuronate + NADPH + H+
-
Homo sapiens L-gulonate + NADP+
-
?