Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2,3-Butanedione | - |
Sus scrofa | |
diethyldicarbonate | - |
Sus scrofa | |
hydroxylamine | - |
Sus scrofa | |
iodoacetic acid | - |
Sus scrofa | |
NaF | - |
Sus scrofa | |
p-chloromercuribenzoate | - |
Sus scrofa | |
Phenobarbital | - |
Sus scrofa | |
Phenylglyoxal | - |
Sus scrofa | |
pyridoxal 5'-phosphate | - |
Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.009 | - |
NADPH | - |
Sus scrofa | |
0.02 | - |
NADP+ | uncoupled reaction | Sus scrofa | |
0.35 | - |
4-nitrobenzaldehyde | - |
Sus scrofa | |
2.6 | - |
Pyridine-3-aldehyde | - |
Sus scrofa | |
4.8 | - |
D-glyceraldehyde | - |
Sus scrofa | |
7.3 | - |
L-gulonate | - |
Sus scrofa | |
8.4 | - |
D-glucuronate | - |
Sus scrofa |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
33000 | - |
SDS-PAGE, gel filtration | Sus scrofa |
36700 | - |
1 * 36700, SDS-PAGE | Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Sus scrofa | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
5.45 | - |
- |
Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-nitrobenzaldehyde + NADPH | - |
Sus scrofa | 4-nitrobenzyl alcohol + NADP+ | - |
r | |
D-glyceraldehyde + NADPH + H+ | - |
Sus scrofa | glycerol + NADP+ | - |
r | |
L-gulonate + NADP+ | - |
Sus scrofa | D-glucuronate + NADPH | - |
? | |
additional information | broad specificity | Sus scrofa | ? | - |
? | |
additional information | reduction of D-glyceraldehyde: pro-4R hydrogen is transferred from NADPH, i.e. A-specific, attacks re face of carbonyl group of the D-glyceraldehyde | Sus scrofa | ? | - |
? | |
pyridine-3-aldehyde + NADPH | - |
Sus scrofa | 3-hydroxypyridine + NADP+ | - |
r |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 36700, SDS-PAGE | Sus scrofa |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | reduction of D-glyceraldehyde: pro-4R hydrogen is transferred from NADPH, i.e. A-specific, attacks re face of carbonyl group of the D-glyceraldehyde | Sus scrofa |