Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
amnion | expression of genes for PGE2 synthesis, with low levels of prostaglandin transporters and dehydrogenase | Homo sapiens | - |
choriodecidua | production of PGE2, PGF2 and PGD2 and high prostaglandin turnover | Homo sapiens | - |
myometrium | in pregnant myometrium, PGI2, PGD2 and PGF2 synthases are highly expressed while prostaglandin dehydrogenase is underexpressed. Myometrium from non-pregnant women has lower levels of prostaglandin synthases and higher levels of prostaglandin dehydrogenase than pregnant myometrium | Homo sapiens | - |
placenta | the prostaglandin synthase expression profile favours production of PGD2, PGE2 and PGF2, with high levels of prostaglandin transporters and catabolic prostaglandin dehydrogenase suggesting rapid prostaglandin turnover | Homo sapiens | - |
uterus | uterine tissues at delivery | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
AKR1B1 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | in cultured myometrial cells there is a dose-dependent stimulatory effect of interleukin 1beta and tumor necrosis factor alpha on PTGS2, PTGES and AKR1B1, i.e.PGF synthase expression | up |