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Literature summary for 1.1.1.188 extracted from

  • Franczak, A.; Woclawek-Potocka, I.; Oponowicz, A.; Kurowicka, B.; Kotwica, G.
    Oxytocin stimulates prostaglandin F2alpha secretion and prostaglandin F synthase protein expression in porcine myometrial tissue (2004), Reprod. Biol., 4, 177-184.
    View publication on PubMed
Search for more literature for 1.1.1.188

Activating Compound

Activating Compound Comment Organism Structure
additional information oxytoxin does not stimulate PGH2 9,11-endoperoxide reductase expression and activity in myometrial tissue of cyclic and early-pregnant sows Sus scrofa
Oxytoxin stimulates enzyme expression and PGD2 11-ketoreductase activity in myometrial tissue of cyclic, but not significantly of early-pregnant, sows, at 0.0001 mM Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
prostaglandin D2 + NADPH + H+ Sus scrofa
-
 prostaglandin 9alpha,11beta-F2 + NADP+
-
 ?
prostaglandin H2 + NADPH + H+ Sus scrofa
-
 prostaglandin F2alpha + NADP+
-
 ?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
 cyclic and early pregnant sows
-

Source Tissue

Source Tissue Comment Organism Textmining
myometrium PGH2 9-,11-endoperoxide reductase activity is expressed and active at early pregnant sows, probably also in cyclic sows Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
prostaglandin D2 + NADPH + H+
-
 Sus scrofa prostaglandin 9alpha,11beta-F2 + NADP+
-
 ?
prostaglandin H2 + NADPH + H+
-
 Sus scrofa prostaglandin F2alpha + NADP+
-
 ?

Synonyms

Synonyms Comment Organism
PGD2 11-ketoreductase
-
 Sus scrofa
PGFS
-
 Sus scrofa
PGH2 9-,11-endoperoxide reductase
-
 Sus scrofa
prostaglandin F synthase
-
 Sus scrofa

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Sus scrofa