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Literature summary for 1.1.1.174 extracted from

  • Davey, J.F.; Trudgill, P.W.
    The metabolism of trans-cyclohexan-1,2-diol by an Acinetobacter species (1977), Eur. J. Biochem., 74, 115-127.
    View publication on PubMed
Search for more literature for 1.1.1.174

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
trans-cyclohexane-1,2-diol + NAD+ Acinetobacter sp. metabolic pathway of trans-cyclohexan-1,2-diol to adipate 2-hydroxycyclohexan-1-one + NADH
-
 r

Organism

Organism UniProt Comment Textmining
Acinetobacter sp.
-
-
-
Acinetobacter sp. TD63
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Acinetobacter sp.

Source Tissue

Source Tissue Comment Organism Textmining
culture condition:cyclohexan-1,2-diol grown cell induction of enzyme formation by trans-cyclohexan-1,2-diol containing medium Acinetobacter sp.
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.85
-
 cell extracts, grown on trans-cyclohexan-1,2-diol Acinetobacter sp.
26.5
-
 partially purified Acinetobacter sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
trans-cyclohexane-1,2-diol + NAD+ metabolic pathway of trans-cyclohexan-1,2-diol to adipate Acinetobacter sp. 2-hydroxycyclohexan-1-one + NADH
-
 r

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
 reduction of 2-hydroxycyclohexan-1-one Acinetobacter sp.
9.5 10 oxidation of trans-cyclohexane-1,2-diol Acinetobacter sp.

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Acinetobacter sp.