Inhibitors | Comment | Organism | Structure |
---|---|---|---|
NADH | uncompetitive inhibition at high concentrations | Homo sapiens | |
oxalate | 10% inhibition at 0.5 mM | Homo sapiens | |
p-chloromercuribenzoate | slight inhibition at 0.02 mM, combined with 0.26 mM SDS | Homo sapiens | |
SDS | slight inhibition at 0.26 mM, combined with 0.02 mM p-chloromercuribenzoate | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.011 | - |
NADH | - |
Homo sapiens | |
2.6 | - |
2-oxoadipate | - |
Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
95000 | - |
gel filtration | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-oxoadipate + NADH | Homo sapiens | highly specific | 2-hydroxyadipate + NAD+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
near homogeneity, chromatography techniques, electrofocusing | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
placenta | - |
Homo sapiens | - |
Storage Stability | Organism |
---|---|
4°C, 25 mM potassium phosphate, pH 7.5, 20% glycerol, no decrease of activity for several months | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-oxoadipate + NADH | highly specific | Homo sapiens | 2-hydroxyadipate + NAD+ | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | - |
Homo sapiens |