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Literature summary for 1.1.1.17 extracted from
- Spatial and developmental differentiation of mannitol dehydrogenase and mannitol-1-phosphate dehydrogenase in Aspergillus niger (2010), Eukaryot. Cell, 9, 1398-1402.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| gene mpdA | Aspergillus niger |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-mannitol 1-phosphate + NAD+ | Aspergillus niger | - |
D-fructose 6-phosphate + NADH + H+ | - |
r |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Aspergillus niger | - |
gene mpdA | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| hypha | - |
Aspergillus niger | - |
| additional information | poor expression of MpdA in conidiospores, expression anaylsis | Aspergillus niger | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 2.8 | - |
premature conidiospores, pH not specified in the publication, temperature not specified in the publication | Aspergillus niger |
| 18.6 | - |
mature conidiospores, pH not specified in the publication, temperature not specified in the publication | Aspergillus niger |
| 68.3 | - |
non-sporulating mycelium, pH not specified in the publication, temperature not specified in the publication | Aspergillus niger |
| 453.9 | - |
sporulating mycelium, pH not specified in the publication, temperature not specified in the publication | Aspergillus niger |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-mannitol 1-phosphate + NAD+ | - |
Aspergillus niger | D-fructose 6-phosphate + NADH + H+ | - |
r | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| mannitol-1-phosphate dehydrogenase | - |
Aspergillus niger |
| MpdA | - |
Aspergillus niger |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Aspergillus niger | |
| NADH | - |
Aspergillus niger | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | the enzyme is involved in the mannitol cycle in the fungus | Aspergillus niger |
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Release 2023.1 (January 2023)
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