Cloned (Comment) | Organism |
---|---|
gene ilvC, complementation of an enzyme-deficient Escherichia coli mutant strain | Corynebacterium glutamicum |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
3.4 | - |
2-oxopantoate | 30°C, pH 7.5 | Corynebacterium glutamicum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-oxopantoate + NADPH | Corynebacterium glutamicum | reaction is part of the D-pantothenate biosynthesis | (R)-pantoate + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Corynebacterium glutamicum | - |
gene ilvC, the enzyme activity in the organism is only encoded by ilvC, a bifunctional enzyme showing acetohydroxyacid isomeroreductase and 2-hydropantoate 2-reductase activity | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0126 | - |
wild-type strain | Corynebacterium glutamicum |
0.0246 | - |
recombinant Escherichia coli mutant strain expresing the enzyme | Corynebacterium glutamicum |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-oxopantoate + NADPH | - |
Corynebacterium glutamicum | (R)-pantoate + NADP+ | - |
? | |
2-oxopantoate + NADPH | reaction is part of the D-pantothenate biosynthesis | Corynebacterium glutamicum | (R)-pantoate + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ilvC | - |
Corynebacterium glutamicum |
ketopantoate reductase | - |
Corynebacterium glutamicum |
KPR | - |
Corynebacterium glutamicum |
More | gene ilvC encodes a acetohydroxyacid isomeroreductase which also shows 2-hydropantoate 2-reductase activity | Corynebacterium glutamicum |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Corynebacterium glutamicum |