Cloned (Comment) | Organism |
---|---|
site-directed mutagenesis, recombinant protein expressed in Escherichia coli GI724 | Rattus norvegicus |
Protein Variants | Comment | Organism |
---|---|---|
K175I | decreased activity against a pteridine substrate and exogenous carbonyl compound | Rattus norvegicus |
S158D | decreased activity against a pteridine substrate and exogenous carbonyl compound | Rattus norvegicus |
S158D/Y171V | double-point mutant does not show any activity towards any substrate | Rattus norvegicus |
Y171V | decreased activity against a pteridine substrate and exogenous carbonyl compound | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
6-(S)-lactoyl-7,8-dihydropterin + NADPH | Rattus norvegicus | - |
6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-phenyl-1,2-propanedione + NADPH | - |
Rattus norvegicus | ? | - |
? | |
6-(S)-lactoyl-7,8-dihydropterin + NADPH | - |
Rattus norvegicus | 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+ | - |
? | |
6-pyruvoyltetrahydropterin + 2 NADPH + 2 H+ | - |
Rattus norvegicus | L-erythro-tetrahydrobiopterin + 2 NADP+ | - |
? | |
acetohexamide + NADPH | - |
Rattus norvegicus | ? | - |
? | |
menadione + NADPH | - |
Rattus norvegicus | ? | - |
? | |
p-nitrobenzaldehyde + NADPH | - |
Rattus norvegicus | p-nitrobenzyl alcohol + NADP+ | - |
? | |
propiophenone + NADPH | - |
Rattus norvegicus | ? | - |
? |