Literature summary for 1.1.1.150 extracted from

Holland, H.L.; Ninniss, R.W.; Brown, F.M.
Stereochemistry of hydrogen loss during C-21 dehydroxylation of tetrahydrodeoxycorticosterone by Eubacterium lentum (1989), Can. J. Chem., 67, 1590-1595.

No PubMed abstract available

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Organism

Organism	UniProt	Comment	Textmining
Bos taurus	-	-	-
Eggerthella lenta	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Bos taurus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5beta-pregnane-3alpha,21-diol-20-one + NAD+	selective for the pro-S position	Bos taurus	5beta-pregnane-3alpha-ol-20,21-dione + NADH + H+	-	?
5beta-pregnane-3alpha,21-diol-20-one + NAD+	selective for the pro-S position	Eggerthella lenta	5beta-pregnane-3alpha-ol-20,21-dione + NADH + H+	-	?

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Release 2023.1 (January 2023)