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Literature summary for 1.1.1.150 extracted from

  • Orr, J.C.; Monder, C.
    The stereochemistry of enzymatic reduction of 21-dehydrocortisol to cortisol (1975), J. Steroid Biochem., 6, 297-299.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Ovis aries aries
-
sheep
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Ovis aries aries
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
11beta,17-dihydroxy-pregn-4-ene-3,20,21-trione + NADH i.e. 21-dehydrocortisol, transfer of the hydrogen to the 21-pro-S position of cortisol Ovis aries aries 11beta,17,21-trihydroxy-pregn-4-ene-3,20-dione + NAD+
-
?

Cofactor

Cofactor Comment Organism Structure
NADH
-
Ovis aries aries