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Literature summary for 1.1.1.146 extracted from

  • Dube, S.; Norby, B.J.; Pattan, V.; Carter, R.E.; Basu, A.; Basu, R.
    11beta-hydroxysteroid dehydrogenase types 1 and 2 activity in subcutaneous adipose tissue in humans: implications in obesity and diabetes (2015), J. Clin. Endocrinol. Metab., 100, E70-E76.
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cortisol + NADP+ Homo sapiens
-
 cortisone + NADPH + H+
-
 r
cortisone + NADPH + H+ Homo sapiens
-
 cortisol + NADP+
-
 r

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adipose tissue
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cortisol + NADP+
-
 Homo sapiens cortisone + NADPH + H+
-
 r
cortisone + NADPH + H+
-
 Homo sapiens cortisol + NADP+
-
 r

Synonyms

Synonyms Comment Organism
11beta-HSD-1
-
 Homo sapiens
11beta-HSD-2
-
 Homo sapiens
11beta-hydroxysteroid dehydrogenase type 1
-
 Homo sapiens
11beta-hydroxysteroid dehydrogenase type 2
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NADP+
-
 Homo sapiens
NADPH
-
 Homo sapiens