Cloned (Comment) | Organism |
---|---|
expressed in HEK-293 cell | Mus musculus |
expressed in HEK-293 cell | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(2S)-5-(acetyloxy)-2-hydroxypentyl acetate | - |
Homo sapiens | |
2-oxopentane-1,5-diyl diacetate | - |
Homo sapiens | |
2-oxopentane-1,5-diyl diacetate | - |
Mus musculus | |
5-hydroxy-4-oxopentyl acetate | - |
Homo sapiens | |
5-hydroxy-4-oxopentyl acetate | - |
Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cortisone + NADPH + H+ | - |
Mus musculus | cortisol + NADP+ | - |
? | |
cortisone + NADPH + H+ | - |
Homo sapiens | cortisol + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
11beta-hydroxysteroid dehydrogenase 1 | - |
Mus musculus |
11beta-hydroxysteroid dehydrogenase 1 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Mus musculus | |
NADP+ | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
additional information | - |
IC50 = 0.0287 mg/ml, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 2-oxopentane-1,5-diyl diacetate | |
additional information | - |
IC50 = 0.0304 mg/ml, pH not specified in the publication, temperature not specified in the publication | Mus musculus | 2-oxopentane-1,5-diyl diacetate | |
additional information | - |
IC50 = 0.0474 mg/ml, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 5-hydroxy-4-oxopentyl acetate | |
additional information | - |
IC50 = 0.0623 mg/ml, pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (2S)-5-(acetyloxy)-2-hydroxypentyl acetate | |
additional information | - |
IC50 = 0.1492 mg/ml, pH not specified in the publication, temperature not specified in the publication | Mus musculus | 5-hydroxy-4-oxopentyl acetate |