Application | Comment | Organism |
---|---|---|
drug development | isozyme 11beta-HSD1 is a target in treatment of metabolic diseases such as diabetes mellitus type 2 or obesity | Homo sapiens |
pharmacology | isozyme 11beta-HSD1 is a target in treatment of metabolic diseases such as diabetes mellitus type 2 or obesity | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
benzothiazole derivatives | specific inhibition of isozyme 11beta-HSD1, inhibitory potency and IC50 values, overview, structure-activity relationship, introduction of a chlor atom at position 4 greatly enhances the inhibitory activity, inhibitory mechanism and enzyme/cofactor interaction analysis from molecular docking studies | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Homo sapiens | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
isozyme 11beta-HSD1 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
11beta-HSD1 | - |
Homo sapiens |
11beta-hydroxysteroid dehydrogenase type 1 | - |
Homo sapiens |