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Literature summary for 1.1.1.145 extracted from

  • Sakai, N.; Tanaka, M.; Takahashi, M.; Fukada, S.; Mason, J.I.; Nagahama, Y.
    Ovarian 3beta-hydroxysteroid dehydrogenase/DELTA5-4-isomerase of rainbow trout: its cDNA cloning and properties of the enzyme expressed in a mammalian cell (1994), FEBS Lett., 350, 309-313.
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
expression in COS-1 monkey kidney tumor cells Oncorhynchus mykiss

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
pregnenolone + NAD(P)+ Oncorhynchus mykiss
-
 pregn-5-en-3,20-dione + NAD(P)H + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Oncorhynchus mykiss
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
ovary
-
 Oncorhynchus mykiss
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3beta,17alpha-dihydroxy-5-pregnen-20-one + NAD(P)+
-
 Oncorhynchus mykiss 17alpha-hydroxypregn-5-ene-3,20-dione + NAD(P)H
-
 ?
pregnenolone + NAD(P)+
-
 Oncorhynchus mykiss pregn-5-en-3,20-dione + NAD(P)H + H+
-
 ?

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Oncorhynchus mykiss