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Literature summary for 1.1.1.14 extracted from

  • Maret, W.
    Human sorbitol dehydrogenase - a secondary alcohol dehydrogenase with distinct pathophysiological roles, pH dependent kinetic studies (1996), Adv. Exp. Med. Biol., , 383-393.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1
-
D-xylulose
-
Homo sapiens
25
-
L-erythrulose
-
Homo sapiens
34
-
D-ribulose
-
Homo sapiens
140
-
D-fructose
-
Homo sapiens
800
-
L-sorbose
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-fructose + NADH + H+
-
Homo sapiens D-sorbitol + NAD+
-
?
D-psicose + NADH
-
Homo sapiens ?
-
?
D-ribulose + NADH
-
Homo sapiens ?
-
?
D-sorbitol + NAD+
-
Homo sapiens D-fructose + NADH + H+
-
?
D-sorbose + NADH low activity Homo sapiens ?
-
?
D-tagatose + NADH
-
Homo sapiens D-galactitol + NAD+
-
?
D-xylulose + NADH
-
Homo sapiens ?
-
?
L-erythrulose + NADH
-
Homo sapiens ?
-
?
L-sorbose + NADH
-
Homo sapiens ?
-
?

pH Stability

pH Stability pH Stability Maximum Comment Organism
6
-
loses zinc at lower pH Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Homo sapiens
NADH
-
Homo sapiens