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Literature summary for 1.1.1.108 extracted from
- Identification of genes required for Pseudomonas aeruginosa carnitine catabolism (2009), Microbiology, 155, 2411-2419.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | strain PA14 mutants with transposon insertions in PA5385 and PA5388 result in the inability of Pseudomonas aeruginosa to grow on carnitine, mutants from the PAO1 transposon insertions in each of the PA5388, PA5387, PA5386 and PA5388 genes are unable to grow on carnitine | Pseudomonas aeruginosa |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pseudomonas aeruginosa | - |
PA5385; PA14 and PAO1 strains | - |
| Pseudomonas aeruginosa | - |
PA5387; PA14 and PAO1 strains | - |
| Pseudomonas aeruginosa | - |
PA5388; PA14 and PAO1 strains | - |
| Pseudomonas aeruginosa | - |
PA5389; PA14 and PAO1 strains | - |
| Pseudomonas aeruginosa | Q9HTH8 | PA5386; PA14 and PAO1 strains | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| carnitine + NAD+ | the PA5388-PA5384 region contains the predicted carnitine dehydrogenase homologue along with other genes required for growth on carnitine. The PA5389 transcription factor (CDHR) is required for growth on carnitine, it is required for induction of the PA5388-PA5384 transcripts in response to carnitine | Pseudomonas aeruginosa | 3-dehydrocarnitine + NADH + H+ | - |
? |  |
| carnitine + NAD+ | the PA5389 transcription factor (CDHR) is required for growth on carnitine, it is required for induction of the PA5388-PA5384 transcripts in response to carnitine | Pseudomonas aeruginosa | 3-dehydrocarnitine + NADH + H+ | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Cdh | - |
Pseudomonas aeruginosa |
| CDHA | - |
Pseudomonas aeruginosa |
| CDHB | - |
Pseudomonas aeruginosa |
| CDHC | - |
Pseudomonas aeruginosa |
| CDHR | - |
Pseudomonas aeruginosa |
| L-(-)-carnitine dehydrogenase | - |
Pseudomonas aeruginosa |
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