Literature summary for 1.1.1.101 extracted from

Opperdoes, F.R.
Localization of the initial steps in alkoxyphospholipid biosynthesis in glycosomes (microbodies) of Trypanosoma brucei (1984), FEBS Lett., 169, 35-39.

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Organism

Organism	UniProt	Comment	Textmining
Trypanosoma brucei	-	stock 427, causative agent of nagana in domestic animals	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
acyldihydroxyacetone phosphate + NADPH	-	Trypanosoma brucei	1-acyl-sn-glycerol 3-phosphate + NADP+	-	?
alkyldihydroxyacetone phosphate + NADPH + H+	-	Trypanosoma brucei	1-alkyl-sn-glycerol 3-phosphate + NADP+	-	?
hexadecyldihydroxyacetone phosphate + NADPH	-	Trypanosoma brucei	1-hexadecyl-sn-glycerol 3-phosphate + NADP+	-	?
palmitoylglycerone phosphate + NADPH	i.e. palmitoyldihydroxyacetone phosphate	Trypanosoma brucei	1-palmitoylglycerol 3-phosphate + NADP+	-	?

Cofactor

Cofactor	Comment	Organism	Structure
NADPH	hydrogen from B-side of nicotinamide ring is transferred to reduce keto substrates	Trypanosoma brucei

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Release 2023.1 (January 2023)