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Literature summary for 1.1.1.1 extracted from

  • Esposito, L.; Bruno, I.; Sica, F.; Raia, C.A.; Giordano, A.; Rossi, M.; Mazzarella, L.; Zagari, A.
    Crystal structure of a ternary complex of the alcohol dehydrogenase from Sulfolobus solfataricus (2003), Biochemistry, 42, 14397-14407.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
apoenzyme and ternary complex of enzyme with NADH and 2-ethoxyethanol bound to each subunit, X-ray diffraction structure determination and analysis at 2.3 A resolution Saccharolobus solfataricus

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ the catalytic active site zinc ion is bound to Glu69 in the apoenzyme state, but not in the ternary complex state Saccharolobus solfataricus

Organism

Organism UniProt Comment Textmining
Saccharolobus solfataricus P39462
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme undergoes a substantial conformational change in the apo-holo transition, accompanied by loop movements at the domain interface Saccharolobus solfataricus ?
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?

Synonyms

Synonyms Comment Organism
ADH
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Saccharolobus solfataricus