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Information on EC 6.4.1.6 - acetone carboxylase

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EC Tree
IUBMB Comments
Requires Mg2+ and ATP. The reaction involves separate phosphorylation of hydrogencarbonate and acetone, forming carboxyphosphate and phosphoenolacetone, respectively, which are combined to form the final product. The enzyme from Xanthobacter sp. strain Py2 also carboxylates butan-2-one to 3-oxopentanoate.
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Archaea
Synonyms
acetone carboxylase, acetone-carboxylating enzyme, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
acetone + CO2 + ATP + 2 H2O = acetoacetate + AMP + 2 phosphate
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PATHWAY SOURCE
PATHWAYS
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