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Disease on EC 6.3.5.2 - GMP synthase (glutamine-hydrolysing)

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Carcinoma
Dynamic compartmentalization of purine nucleotide metabolic enzymes at leading edge in highly motile renal cell carcinoma.
Carcinoma, Hepatocellular
Biochemical pharmacology of acivicin in rat hepatoma cells.
Enzymes of purine metabolism in cancer.
Guanosine-5'-phosphate synthetase and guanosine-5'-phosphate kinase in rat hepatomas and kidney tumors.
Inactivation by acivicin of rat brain CTP and GMP synthetases and depression of CTP and GTP concentrations.
Methotrexate decreases thymidine kinase activity.
Oncolytic activity and mechanism of action of a novel L-cysteine derivative, L-cysteine, ethyl ester, S-(N-methylcarbamate) monohydrochloride.
Recovery of the activities of IMP dehydrogenase and GMP synthase after treatment with tiazofurin and acivicin in hepatoma cells in vitro.
Carcinoma, Renal Cell
Dynamic compartmentalization of purine nucleotide metabolic enzymes at leading edge in highly motile renal cell carcinoma.
Dehydration
Intra-specific variations in expression of stress-related genes in beech progenies are stronger than drought-induced responses.
Infections
GMP Synthase Is Required for Virulence Factor Production and Infection by Cryptococcus neoformans.
Inflammatory Bowel Diseases
Nonsynonymous Polymorphism in Guanine Monophosphate Synthetase Is a Risk Factor for Unfavorable Thiopurine Metabolite Ratios in Patients With Inflammatory Bowel Disease.
Insulin Resistance
Discovery of a metabolic pathway mediating glucose-induced desensitization of the glucose transport system. Role of hexosamine biosynthesis in the induction of insulin resistance.
Leukemia
Mechanism of resistance of a variant of P388 leukemia to L-(alpha S,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (acivicin).
Liver Neoplasms
Proteomic Analysis Reveals GMP Synthetase as p53 Repression Target in Liver Cancer.
Mycoses
GMP Synthase Is Required for Virulence Factor Production and Infection by Cryptococcus neoformans.
Neoplasms
Guanosine-5'-phosphate synthetase and guanosine-5'-phosphate kinase in rat hepatomas and kidney tumors.
Mycophenolic acid and its mechanism of action in cancer and psoriasis.
Oncolytic activity and mechanism of action of a novel L-cysteine derivative, L-cysteine, ethyl ester, S-(N-methylcarbamate) monohydrochloride.
Quantification of Isotope Encoded Proteins in 2-D Gels Using Surface Enhanced Resonance Raman.
Regulation of GTP biosynthesis.
Targets and markers of selective action of tiazofurin.
Prostatic Neoplasms
Inhibition of guanosine monophosphate synthetase (GMPS) blocks glutamine metabolism and prostate cancer growth.
Sarcoma, Yoshida
Purification and characterization of GMP synthetase from Yoshida sarcoma ascites cells.
Starvation
DegS-DegU and ComP-ComA modulator-effector pairs control expression of the Bacillus subtilis pleiotropic regulatory gene degQ.
Expression of kinA and kinB of Bacillus subtilis, Necessary for Sporulation Initiation, Is under Positive Stringent Transcription Control.
Guanosine-5'-phosphate synthetase and guanosine-5'-phosphate kinase in rat hepatomas and kidney tumors.
Tuberculosis
Biochemical characterization of recombinant guaA-encoded guanosine monophosphate synthetase (EC 6.3.5.2) from Mycobacterium tuberculosis H37Rv strain.
Characterization of the D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase gene (xfp) from Bifidobacterium lactis.
Glutamine amidotransferase activity of NAD+ synthetase from Mycobacterium tuberculosis depends on an amino-terminal nitrilase domain.