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ATP + adenosylcobyric acid + (R)-1-aminopropan-2-ol = ADP + phosphate + adenosylcobinamide
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ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate = ADP + phosphate + adenosylcobinamide phosphate
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate = ADP + phosphate + adenosylcobinamide phosphate
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ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate = ADP + phosphate + adenosylcobinamide phosphate
this enzyme forms part of the anaerobic cobalamin biosynthesis pathway, one of the substrates for this reaction, (R)-1-aminopropan-2-yl phosphate, is produced by CobD, EC 4.1.1.81, threonine phosphate decarboxylase
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ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate = ADP + phosphate + adenosylcobinamide phosphate
this enzyme forms part of the anaerobic cobalamin biosynthesis pathway, one of the substrates for this reaction, (R)-1-aminopropan-2-yl phosphate, is produced by CobD, EC 4.1.1.81, threonine phosphate decarboxylase
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Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
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ATP + adenosylcobyric acid + (R)-1-aminopropan-2-ol
ADP + phosphate + adenosylcobinamide
-
-
-
-
?
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate
ADP + phosphate + adenosylcobinamide phosphate
ATP + ethanolamine phosphate
norcobalamin + ?
additional information
?
-
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate
ADP + phosphate + adenosylcobinamide phosphate
-
-
-
-
?
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate
ADP + phosphate + adenosylcobinamide phosphate
-
the enzyme is involved in the cobinamide salvaging pathways in bacteria and archaea, phylogenetic correlation, overview
-
-
?
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate
ADP + phosphate + adenosylcobinamide phosphate
-
-
-
-
?
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate
ADP + phosphate + adenosylcobinamide phosphate
-
the enzyme is involved in the cobinamide salvaging pathways in bacteria and archaea, phylogenetic correlation, overview
-
-
?
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate
ADP + phosphate + adenosylcobinamide phosphate
-
-
-
-
?
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate
ADP + phosphate + adenosylcobinamide phosphate
-
the enzyme is involved in the cobinamide salvaging pathways in bacteria and archaea, phylogenetic correlation, overview
-
-
?
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate
ADP + phosphate + adenosylcobinamide phosphate
-
-
-
-
?
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate
ADP + phosphate + adenosylcobinamide phosphate
-
the enzyme is involved in the the cobinamide salvaging pathways in bacteria and archaea, phylogenetic correlation, overview
-
-
?
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate
ADP + phosphate + adenosylcobinamide phosphate
-
-
-
-
?
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate
ADP + phosphate + adenosylcobinamide phosphate
-
amide bond formation, the substrate for CbiB is not aminopropanol but its phosphate
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-
?
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate
ADP + phosphate + adenosylcobinamide phosphate
-
the enzyme is involved in the the cobinamide salvaging pathways in bacteria and archaea, Salmonella enterica serovar Typhimurium is unable to salvage cobinamide due to a lack of CbiZ, AdoCbi amidohydrolase, phylogenetic correlation, overview
-
-
?
ATP + ethanolamine phosphate
norcobalamin + ?
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-
-
?
ATP + ethanolamine phosphate
norcobalamin + ?
-
-
-
?
additional information
?
-
-
inactivation of cobD, encoding threonine-phosphate decarboxylase, EC 4.1.1.81, prevents salvaging of Cbi, because AdoCby is not converted to AdoCbi-P in the absence of aminopropanolphosphate, but addition of 1-amino-2-propanol to the medium can reverse the effect
-
-
?
additional information
?
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-
CbiB is involved in a salvaging pathway for cobinamide
-
-
?
additional information
?
-
-
inactivation of cobD, encoding threonine-phosphate decarboxylase, EC 4.1.1.81, prevents salvaging of Cbi, because AdoCby is not converted to AdoCbi-P in the absence of aminopropanolphosphate, but addition of 1-amino-2-propanol to the medium can reverse the effect
-
-
?
additional information
?
-
-
CbiB is involved in a salvaging pathway for cobinamide
-
-
?
additional information
?
-
-
inactivation of cobD, encoding threonine-phosphate decarboxylase, EC 4.1.1.81, prevents salvaging of Cbi, because AdoCby is not converted to AdoCbi-P in the absence of aminopropanolphosphate, but addition of 1-amino-2-propanol to the medium can reverse the effect
-
-
?
additional information
?
-
-
inactivation of cobD, encoding threonine-phosphate decarboxylase, EC 4.1.1.81, prevents salvaging of Cbi, because AdoCby is not converted to AdoCbi-P in the absence of aminopropanolphosphate, but addition of 1-amino-2-propanol to the medium can reverse the effect
-
-
?
additional information
?
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CbiB is involved in the anaerobic cobalamin/cobinamide biosynthesis pathway
-
-
?
additional information
?
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L-threonine-phosphate is not a substrate
-
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?
additional information
?
-
L-threonine-phosphate is not a substrate
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?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-ol
ADP + phosphate + adenosylcobinamide
-
-
-
-
?
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate
ADP + phosphate + adenosylcobinamide phosphate
additional information
?
-
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate
ADP + phosphate + adenosylcobinamide phosphate
-
the enzyme is involved in the cobinamide salvaging pathways in bacteria and archaea, phylogenetic correlation, overview
-
-
?
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate
ADP + phosphate + adenosylcobinamide phosphate
-
the enzyme is involved in the cobinamide salvaging pathways in bacteria and archaea, phylogenetic correlation, overview
-
-
?
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate
ADP + phosphate + adenosylcobinamide phosphate
-
the enzyme is involved in the cobinamide salvaging pathways in bacteria and archaea, phylogenetic correlation, overview
-
-
?
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate
ADP + phosphate + adenosylcobinamide phosphate
-
the enzyme is involved in the the cobinamide salvaging pathways in bacteria and archaea, phylogenetic correlation, overview
-
-
?
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate
ADP + phosphate + adenosylcobinamide phosphate
-
-
-
-
?
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate
ADP + phosphate + adenosylcobinamide phosphate
-
the enzyme is involved in the the cobinamide salvaging pathways in bacteria and archaea, Salmonella enterica serovar Typhimurium is unable to salvage cobinamide due to a lack of CbiZ, AdoCbi amidohydrolase, phylogenetic correlation, overview
-
-
?
additional information
?
-
-
inactivation of cobD, encoding threonine-phosphate decarboxylase, EC 4.1.1.81, prevents salvaging of Cbi, because AdoCby is not converted to AdoCbi-P in the absence of aminopropanolphosphate, but addition of 1-amino-2-propanol to the medium can reverse the effect
-
-
?
additional information
?
-
-
CbiB is involved in a salvaging pathway for cobinamide
-
-
?
additional information
?
-
-
inactivation of cobD, encoding threonine-phosphate decarboxylase, EC 4.1.1.81, prevents salvaging of Cbi, because AdoCby is not converted to AdoCbi-P in the absence of aminopropanolphosphate, but addition of 1-amino-2-propanol to the medium can reverse the effect
-
-
?
additional information
?
-
-
CbiB is involved in a salvaging pathway for cobinamide
-
-
?
additional information
?
-
-
inactivation of cobD, encoding threonine-phosphate decarboxylase, EC 4.1.1.81, prevents salvaging of Cbi, because AdoCby is not converted to AdoCbi-P in the absence of aminopropanolphosphate, but addition of 1-amino-2-propanol to the medium can reverse the effect
-
-
?
additional information
?
-
-
inactivation of cobD, encoding threonine-phosphate decarboxylase, EC 4.1.1.81, prevents salvaging of Cbi, because AdoCby is not converted to AdoCbi-P in the absence of aminopropanolphosphate, but addition of 1-amino-2-propanol to the medium can reverse the effect
-
-
?
additional information
?
-
-
CbiB is involved in the anaerobic cobalamin/cobinamide biosynthesis pathway
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
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Warren, M.J.; Raux, E.; Schubert, H.L.; Escalante-Semerena, J.C.
The biosynthesis of adenosylcobalamin (vitamin B12)
Nat. Prod. Rep.
19
390-412
2002
Salmonella enterica
brenda
Cheong, C.G.; Bauer, C.B.; Brushaber, K.R.; Escalante-Semerena, J.C.; Rayment, I.
Three-dimensional structure of the L-threonine-O-3-phosphate decarboxylase (CobD) enzyme from Salmonella enterica
Biochemistry
41
4798-4808
2002
Salmonella enterica
brenda
Woodson, J.D.; Zayas, C.L.; Escalante-Semerena, J.C.
A new pathway for salvaging the coenzyme B12 precursor cobinamide in archaea requires cobinamide-phosphate synthase (CbiB) enzyme activity
J. Bacteriol.
185
7193-7201
2003
Halobacterium sp., Halobacterium sp. NRC-1
brenda
Zayas, C.L.; Claas, K.; Escalante-Semerena, J.C.
The CbiB protein of Salmonella enterica is an integral membrane protein involved in the last step of the de novo corrin ring biosynthetic pathway
J. Bacteriol.
189
7697-7708
2007
Salmonella enterica (Q05600), Salmonella enterica LT2 (Q05600)
brenda
Gray, M.J.; Tavares, N.K.; Escalante-Semerena, J.C.
The genome of Rhodobacter sphaeroides strain 2.4.1 encodes functional cobinamide salvaging systems of archaeal and bacterial origins
Mol. Microbiol.
70
824-836
2008
Salmonella enterica, Halobacterium sp., Methanosarcina mazei, Cereibacter sphaeroides, Halobacterium sp. NRC-1
brenda